research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
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research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Pathophysiological Mechanisms Implicated in Postpartum Depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Targeting to the Hair Follicles: Current Status and Potential
Hair follicles are promising targets for delivering drugs effectively.
research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men
New 5% minoxidil foam effectively promotes hair growth and is safe for use.
research The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women
Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Physiologic Skin Changes in Pregnancy
Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.
research Microneedles as the Technique of Drug Delivery Enhancement in Diverse Organs and Tissues
Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
research Mechanical and Biological Properties of Keratose Biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
research Activating Wnt/β-Catenin Signaling Pathway for Disease Therapy: Challenges and Opportunities
Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Vitamin D and the Skin: Focus on a Complex Relationship
Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.
research Transplantation Immunology: Solid Organ and Bone Marrow
Transplant success has improved with better immunosuppressive drugs and donor matching.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Hair Anatomy for the Clinician
Understanding hair follicle anatomy helps diagnose hair disorders.
research Hair Follicle-Specific Keratins And Their Diseases
Only a few hair-specific keratins are linked to inherited hair disorders.
research Classification and Management of Skin, Hair, Nail, and Mucosal Side Effects of Epidermal Growth Factor Receptor Inhibitors
EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.
research The Psychology of Hair Loss and Its Implications for Patient Care
Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.
research Hormone Replacement Therapy and the Skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Topical Minoxidil in Early Male Pattern Baldness
Minoxidil promotes hair growth in male pattern baldness.
research The Origin of Citrulline-Containing Proteins in the Hair Follicle and the Chemical Nature of Trichohyalin, an Intracellular Precursor
research The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women
Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research The Influence of Androgens on Insulin Resistance
Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
research Facial Feminization Surgery: Current State of the Art
Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Electrolysis: Observations from 13 Years and 140,000 Hours of Experience
Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.
research Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream
The microemulsion delivered the dye deeper into the skin than the cream.