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The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Long-term minoxidil use can cause pseudoacromegaly, but stopping it improves symptoms.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

The vitamin D receptor can work without its usual activating molecule.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Minoxidil reduces lysine hydroxylase in skin cells.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

Low androgen levels can still cause female pattern hair loss.

A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.

Minoxidil boosts hair growth by activating PGHS-1.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.