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research Regulation of somatic cell reprogramming through inducible mir-302 expression

308 citations , September 2010 in “Nucleic acids research”

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

research Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity

200 citations , March 2023 in “Nature Reviews Molecular Cell Biology”

This review discusses the role and regulation of quiescent adult stem cells in tissue maintenance and repair, focusing on molecular mechanisms and their implications for regenerative medicine, but reports no new clinical results.

research Regulation of Involucrin Gene Expression

138 citations , June 2004 in “Journal of Investigative Dermatology”

This review discusses the regulation of involucrin gene expression, focusing on transcription factors and signaling pathways, and reports no new experimental findings.

research Regulation of Keratin Gene Expression in Hair Follicle Differentiation^a

98 citations , December 1991 in “Annals of the New York Academy of Sciences”

This study found that conserved DNA motifs and expression patterns in keratin genes suggest functional regulatory similarities in hair follicle differentiation across different mammalian species.

research Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial–Mesenchymal Interactions

92 citations , April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that keratin 9 expression in nonpalmoplantar keratinocytes can be induced by signals from palmoplantar fibroblasts, potentially enabling the use of nonpalmoplantar epidermis to treat palmoplantar wounds.

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Community Join

5 / 819 results

community Relationship between Dandruff and Hair loss?

6 upvotes 3 weeks ago

Dandruff may contribute to hair shedding, but there's no direct correlation; stress and scalp inflammation can also impact hair health. Treatments like Ketoconazole shampoo are used to manage dandruff and potentially reduce shedding.

community Fluridil/Eucapil UAE customs regulation

in Chat 1 year ago

A user in the UAE is facing customs issues with ordering Fluridil (Eucapil) and is considering ordering smaller quantities or switching to Pyrilutamide. They are also using finasteride daily to maintain hair and are unsure of Fluridil's effectiveness.

community Table of the relationship between physical exercise and the regeneration of the deminiaturized hair follicle

45 upvotes 1 year ago

Exercise, especially leg workouts, combined with finasteride and minoxidil, may enhance hair regrowth. Cold exposure, like cold showers, might further boost results.

community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

46 upvotes 1 month ago

Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

24 upvotes 1 year ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

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Learn

5 / 801 results

learn Hair Transplant

What is NeoGraft in relation to hair transplant? NeoGraft is an automated FUE hair transplant system that enhances accuracy and speed.

learn Dutasteride

Can I use dutasteride without a prescription? All about its sale and regulations. Dutasteride requires a prescription and cannot be used without medical supervision.

learn Thymosin Beta 4

What is Thymosin Beta 4, and why is it being researched in relation to hair follicle function and regeneration? Thymosin Beta 4 is a peptide being researched for its potential to enhance hair follicle regeneration.

learn Tofacitinib

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

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