June 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.
Verteporfin reduces scar tissue in hair transplants but doesn't significantly regrow hairfollicles. More testing is needed to determine its effectiveness.
Finasteride prevents further hair loss by blocking DHT, while minoxidil stimulates hair growth by prolonging the active phase of hairfollicles. Stopping minoxidil can lead to loss of regrownhair because finasteride does not address the same growth mechanism.
Hairfollicles can potentially produce more hair strands with treatments like Minoxidil and finasteride. Notable improvements in hair density are possible, but achieving multiple strands per follicle is uncertain.
PP405 is considered as a potential hair regrowth treatment, but users are skeptical due to past product failures. They compare it to Minoxidil and Finasteride, questioning its effectiveness and the intentions of pharmaceutical companies.