research Differential Metabolic Adaptations Define Responses of Winner and Loser Oncogenic Mutant Stem Cells in Skin Epidermis In Vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
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research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
research Quaternary Ammonium Iminofullerenes Improve Root Growth of Oxidative-Stress Maize Through ASA-GSH Cycle Modulating Redox Homeostasis of Roots and ROS-Mediated Root-Hair Elongation
Quaternary ammonium iminofullerenes help maize roots grow better under stress by reducing oxidative damage.
research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Analysis of Chemotherapy-Induced Peripheral Neuropathy Using the Japanese Adverse Drug Event Report Database
Certain cancer drugs are strongly linked to nerve damage, requiring close monitoring and early treatment.
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5 / 27 resultscommunity 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2
Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.
community My DHT levels while being on DUT for a year
The conversation discusses the ineffectiveness of tablet forms of dutasteride for hair loss due to poor absorption compared to soft gel capsules. It suggests switching to FDA-approved soft gel capsules for better results, as tablets may not adequately suppress DHT levels.
community PSA: You guys are paying way too much for your Finasteride and Minoxidil. Here's the cheapest I've found.
Finasteride and minoxidil can be obtained cheaply through Mark Cuban's Cost Plus Drugs and Costco's Kirkland brand, respectively, costing about $7.53/month combined. Amazon's RXPass and virtual visits at Dr. B. offer additional savings.
community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.
A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.
community Bile Acid-Mediated DHT Dysregulation Hypothesis
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.