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research Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth.

34 citations , September 1997 in “Acta Dermato Venereologica”

This study found that RXR agonists stimulated human hair follicle growth and survival in vitro, suggesting potential for promoting hair growth in humans.

research Complete remission of alopecia areata under treatment of chronic hand eczema with alitretinoin

8 citations , January 2013 in “European Journal of Dermatology”

This article reviews the use of alitretinoin for corticosteroid-refractory chronic hand eczema and explores its potential therapeutic benefits in other skin conditions, but reports no clinical results.

research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways

24 citations , September 2005 in “Journal of Cellular Biochemistry”

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

research Prediction and Demonstration of Retinoic Acid Receptor Agonist Ch55 as an Antifibrotic Agent in the Dermis

3 citations , February 2023 in “Journal of Investigative Dermatology”

Ch55 may help reduce skin scarring and fibrosis.

research The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events.

44 citations , May 1998 in “PubMed”

In this study, a specific retinoic acid receptor antagonist caused severe craniofacial anomalies in mouse fetuses when administered early in pregnancy, but not limb anomalies, highlighting developmental stage-specific roles of retinoic acid.

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community Is tazarotene potentially better than tretinoin in combination with topical minoxidil?

1 upvotes 11 months ago

Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.

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