December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
104 citations
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May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
30 citations
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June 1988 in “Journal of Steroid Biochemistry” Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
9 citations
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December 1996 in “Cell Biology and Toxicology” The study investigated the paracrine activity of vascular endothelial growth factor (VEGF) produced by hair dermal papilla cells (DPC) on fetal bovine aortic endothelial cells (FBAEC). The researchers exposed FBAEC to conditioned medium from DPC cultures and observed dose-dependent stimulation of FBAEC growth and migration. Additionally, radioreceptor assays demonstrated competitive VEGF binding in FBAEC, indicating that DPC-secreted VEGF could influence endothelial cell behavior, suggesting a role in hair follicle vascularization.
277 citations
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July 2002 in “Molecular Endocrinology” Removing part of the vitamin D receptor stops vitamin D from working properly.