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GlossaryRenin-Angiotensin System (RAAS)

hormone system regulating blood pressure and fluid balance

The Renin-Angiotensin System (RAS), also known as the Renin-Angiotensin-Aldosterone System (RAAS), is a hormone system that regulates blood pressure and fluid balance in the body. When blood pressure drops, the kidneys release the enzyme renin, which triggers a cascade of reactions leading to the production of angiotensin II, a potent vasoconstrictor that increases blood pressure and stimulates the release of aldosterone from the adrenal glands, promoting sodium and water retention.

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research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen

13 citations , December 2012 in “Frontiers in bioscience”

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

32 citations , January 2012 in “Clinical & Developmental Immunology”

Targeting CD200 could be a new treatment for rheumatoid arthritis.

research Vulvar Discomfort in a 10-Year-Old Girl

1 citations , August 2021 in “Pediatrics in review”

A 10-year-old girl had genital pain from a small, red, crusty mass on her labia.

research EP03: An Audit of Glucocorticoid Prescription in Patients with Giant Cell Arteritis

April 2020 in “Rheumatology”

Many patients with Giant Cell Arteritis did not follow their steroid treatment plans properly.

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community P-1075: a BETTER version of Minoxidil

in Research/Science 3 weeks ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community New 2025 study: high dose oral minoxidil (up to 10mg)

in Research/Science 80 upvotes 1 month ago

High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

community The Fear of Oral Minoxidil is Overblown

in Research/Science 259 upvotes 4 months ago

Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.