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5 / 1000+ results![Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque](/images/research/624c495f-619c-4f24-abd3-bacd323c27f7/small/12598.jpg)
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
![Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque<sup>1</sup>](/images/research/bfbc2669-6de8-456c-a334-f096d9e84de1/small/12619.jpg)
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque1
Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
![Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen](/images/research/4bf69b4d-2b2e-400c-87f0-4798d75362c9/small/12602.jpg)
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
![RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism](/images/research/22c72f57-74fc-4f8d-b13d-4cb48dc748c4/small/2025.jpg)
research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.
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5 / 1000+ resultscommunity I am having Success with RU58841 and 1mm Derma Roller
A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.
community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc
Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.
community How can ru-58841 be effective if pyrilutamide failed phase 3 clinical trials?
The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.
community Progress photos - 33 male - 0.5mg oral dut once a day (9.5 months) - 2.5mg oral min twice a day (9.5 months) - 2% Nizoral shampoo twice a week (2.5 months) - 5% RU-58841 once a day (1 month)
A 33-year-old male shared progress photos after using 0.5mg oral dutasteride daily for 9.5 months, 2.5mg oral minoxidil twice daily for 9.5 months, 2% Nizoral shampoo twice a week for 2.5 months, and 5% RU-58841 once daily for 1 month. A commenter noted the impressive progress and inquired about the absence of dermarolling.
community Soo.. uhh.. one year... wondering when Dutasteride is going to stop hair loss
User has been on finasteride and switched to Dutasteride 6 months ago, using minoxidil, tretinoin, microneedling, and RU-58841, but still experiencing hair loss. Advice given includes waiting 6-18 months for Dutasteride results and checking if it's definitely MPB.