This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.
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November 2022 in “Journal of biomedical materials research. Part B, Applied biomaterials” This study demonstrated that human hair keratins have strong antioxidative properties, providing protection against oxidative stress in human dermal fibroblasts, suggesting their potential as antioxidizing supplements.
April 2023 in “Dermatology practical & conceptual” This study concluded that lenalidomide significantly induces the proliferation and migration of melanocyte stem cells, enhancing their differentiation into functional melanocytes in a mouse model.
November 2025 in “Figshare” In this study, six metabolic reprogramming-related genes, including SQSTM1, were significantly associated with alopecia areata, with elevated SQSTM1 mRNA and protein levels observed in affected hair follicles compared to healthy controls.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, RNA integrity in horse hair follicles stored at various conditions in RNAlater® was maintained, showing that storing them at cool or room temperature for up to a week does not compromise RNA quality or concentration.