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community What is everyone's assessment of pyrilutamide 1.0% topical as a adjunct treatment?

5 upvotes 3 months ago

The conversation discusses the use of pyrilutamide as an adjunct treatment for hair loss, particularly for those already using finasteride and minoxidil. Users share mixed experiences, with some reporting side effects like numbness and gynecomastia, while others note its potential benefits in reducing shedding and scalp itchiness.

community Pyrilutamide for non-5AR users?

in Treatment 10 upvotes 1 year ago

Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

community Is this the best current Stack that doesnt involve FIN/DUT?

in Treatment 7 upvotes 2 years ago

The post and conversation are about a hair loss treatment stack without finasteride or dutasteride. The suggested treatments include Alfatradiol, Koshine826, Ketoconazole lotion, Minoxidil, microneedling, Tretinoin, and Stemoxydine.

community Looking for KX826 (pyrilutamide) success stories

in Treatment 12 upvotes 2 years ago

A user ordered pyrilutamide (KX826) to stop hair loss and is seeking success stories. Replies indicate that it's too early to evaluate the product's effectiveness, as it takes several months to see results.

community Keep your heads up bros, don't let balding affect your mental

64 upvotes 7 months ago

Hair loss can cause psychological distress, but maintaining optimism and self-improvement is crucial. Treatments like minoxidil, finasteride, and potential new options like clascoterone offer hope, though side effects can occur.

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Research

5 / 209 results

research Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration

9 citations , September 2017 in “Nanoscale Research Letters”

This study found that combining TIMP-1 with graphene oxide promoted skin tissue regeneration in rats and provided sustained release of TIMP-1 over 40 days.

research The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial

57 citations , August 2003 in “British Journal of Dermatology”

This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.

research Enhanced cutaneous wound healing by functional injectable thermo-sensitive chitosan-based hydrogel encapsulated human umbilical cord-mesenchymal stem cells

48 citations , July 2019 in “International Journal of Biological Macromolecules”

This study found that a newly developed injectable hydrogel combined with human umbilical cord-mesenchymal stem cells significantly accelerated wound healing and reduced inflammation in full-thickness cutaneous wounds.

research 5α-reductase activity in the prostate

237 citations , December 2001 in “Urology”

This review discusses the role of 5α-reductase in prostate development and BPH, and reports no new clinical results; ongoing trials are exploring dual isozyme inhibitors for improved treatment efficacy.

research Acne as a chronic systemic disease

71 citations , November 2013 in “Clinics in Dermatology”

This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

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