research Studies on Basal Cell Carcinoma: Role of Human Homologue of Drosophila Patched Gene
PTCH gene mutations contribute to basal cell carcinoma development.
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5 / 134 resultsresearch Skin Precancer: Progression and Genetic Factors
Sun exposure and genetics increase skin cancer risk from precancerous lesions.
research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice
Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
research Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Spreading of Isolated Ptch Mutant Basal Cell Carcinoma Precursors Is Physiologically Suppressed and Counteracts Tumor Formation in Mice
External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.
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