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research Can we identify a post‐Serenoa syndrome (PSS)? A case series on sexual and psychiatric side effects of Serenoa repens

January 2026 in “British Journal of Clinical Pharmacology”

In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.

research Psychiatric and sexual dysfunction warnings strengthened for finasteride and dutasteride

January 2026 in “Pharmaceutical journal/The pharmaceutical journal”

The MHRA announced on 11 May 2026 that it will update the product information for finasteride and dutasteride to include more details on potential psychiatric and sexual side effects, following a review of existing evidence.

research Acne vulgaris

12 citations , May 2017 in “Medicine”

This article provides an overview of acne vulgaris, discussing its causes, presentation, and psychosocial impact, but it reports no new research findings or clinical results.

research Care of the transgender patient: the role of the gynecologist

86 citations , May 2013 in “American journal of obstetrics and gynecology”

This article reviews the care of transgender patients, encompassing diagnosis, treatment options, and challenges in health care access, but does not present new research findings; the authors emphasize the critical role of providers in addressing transgender health needs.

research High‐dose pulsed corticosteroid therapy combined with methotrexate for severe alopecia areata of childhood

15 citations , May 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

This article is a letter to the editor about high-dose pulsed corticosteroid therapy combined with methotrexate for severe childhood alopecia areata and provides no new clinical results.

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community Common hair-loss drug consistently associated with higher rates of psychiatric harm

in Research/Science 183 upvotes 1 year ago

Finasteride and dutasteride can cause psychiatric side effects like depression and suicidal thoughts in some users, especially those with a history of mental health issues. While some users experience positive hair growth results, others face severe psychological effects, raising concerns about their safety and the need for careful monitoring.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community Heads up for EU Fin users: Finasteride prescription has been toughened up in France

in Finasteride/Dutasteride 106 upvotes 5 months ago

Finasteride prescriptions in France now require an annual certificate acknowledging psychiatric and sexual risks, as the European Medicines Agency recognizes these risks. The conversation discusses the potential mental health effects of Finasteride, with some users reporting side effects and others questioning the statistical significance of these findings.

community Hair Transplant Issues & Hair Loss Medication Side Effects - Similar Experiences

in Basic Questions 187 upvotes 4 months ago

The user experienced long-term pain after an FUE hair transplant and is considering Kenacort injections for relief. They also reported brain fog, dizziness, and anxiety after stopping minoxidil and finasteride, and are currently using PRP, microneedling, and rosemary oil for hair maintenance.

community I have tried every hairloss option between shaving and wigs. Considering retrying fin because depression medication also has sexual side effects and hairloss has driven me to almost need them. Every hairloss option I have tried has a "dealbreaker" caveat and so I am forced to choose one of the below

4 upvotes 10 years ago

The user is struggling with hair loss and has tried treatments like finasteride, minoxidil, and hair systems, each with drawbacks. They are considering retrying finasteride before a hair transplant and are advised to seek therapy for mental health support.

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Learn

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learn Saw Palmetto

Palm-berry extract taken as a supplement

learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn Dutasteride

5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

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