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GlossaryPruritic Papular Eruption

itchy skin condition with small, raised bumps

Pruritic Papular Eruption (PPE) is a skin condition characterized by the appearance of small, itchy bumps (papules) on the skin. It is commonly seen in individuals with HIV/AIDS but can also occur in other contexts. The exact cause is not well understood, but it is thought to be related to immune system dysfunction. Treatment typically involves managing the underlying condition and using topical or systemic medications to alleviate itching and inflammation.

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research Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part III

15 citations, November 2002 in “Cardiology in Review”

Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.

research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis

7 citations, July 2013 in “InTech eBooks”

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

research Cutaneous Reactions to Recombinant Cytokine Therapy

105 citations, September 1995 in “Journal of The American Academy of Dermatology”

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

research Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

7 citations, August 2020 in “Scientifica”

Most HIV-positive patients had skin problems, and conditions like oral thrush and boils were linked to weaker immune systems.

research Clinical Aspects and Spectrum of Illness of Toxic Shock Syndrome: Overview

77 citations, January 1989 in “Clinical Infectious Diseases”

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

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