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research Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin

28 citations , December 2015 in “Journal of biological chemistry/The Journal of biological chemistry”

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

research The CAP1/Prss8 Catalytic Triad Is Not Involved in PAR2 Activation and Protease Nexin-1 (PN-1) Inhibition

14 citations , August 2014 in “The FASEB Journal”

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

research The Mouse Frizzy (Fr) And Rat ‘Hairless’ (FrCR) Mutations Are Natural Variants Of Protease Serine S1 Family Member 8 (Prss8)

28 citations , February 2010 in “Experimental Dermatology”

The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.

research Genetics of Inherited Ichthyoses and Related Diseases

66 citations , January 2020 in “Acta Dermato Venereologica”

New genetic variants linked to inherited ichthyoses were identified, offering insights for potential gene therapy.

research A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features

196 citations , March 2016 in “Nature Communications”

Genetic factors influence hair traits like shape, color, and greying in Latin Americans.

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