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Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2

research Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2

21 citations , November 2017 in “Scientific Reports”

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

research Mapping the Expression of Epithelial Hair Follicle Stem Cell-Related Transcription Factors LHX2 and SOX9 in the Human Hair Follicle

33 citations , March 2015 in “Experimental Dermatology”

LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.

research Mapping Cell Dynamics in Human Ex Vivo Hair Follicles Suggests Pulling Mechanism of Hair Growth

November 2025 in “Nature Communications”

Hair growth may involve a pulling force from the outer root sheath.

research CDK4/6 Inhibition Mitigates Stem Cell Damage in a Novel Model for Taxane-Induced Alopecia

58 citations , September 2019 in “EMBO Molecular Medicine”

CDK4/6 inhibitors can protect hair cells from chemotherapy damage.

research Aging of the Hair Follicle Pigmentation System

75 citations , January 2009 in “International journal of trichology”

Hair grays due to oxidative stress and fewer functioning melanocytes.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.