November 2023 in “Research Square (Research Square)” Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
March 2024 in “The journal of sexual medicine” Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.
11 citations,
December 2017 in “Orphanet Journal of Rare Diseases” A novel homozygous p.Asp482Asn mutation in the ST14 gene, encoding the serine protease matriptase, was identified in a patient with ichthyosis-hypotrichosis syndrome (IHS) from a cohort of 180 ichthyosis patients. This mutation affected a critical ligand-binding domain of matriptase, expanding the known spectrum of IHS pathology. Histological and ultrastructural analyses revealed new features of the disorder, correlating genotypic and phenotypic characteristics and underscoring the clinical significance of the Asp482 residue in matriptase activation.
1 citations,
January 2016 in “Asian-Australasian journal of animal sciences” The protein Gnαs is found more in black mice than white mice and may influence their coat color.
53 citations,
January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.