32 citations
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April 2013 in “Anais Brasileiros de Dermatologia” The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
105 citations
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December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
November 2025 in “American Journal of Case Reports” This case study presents an 8-year-old girl with acrodermatitis enteropathica (AE) complicated by Kaposi’s varicelliform eruption (KVE), linked to novel compound heterozygous variants of the SLC39A4 gene. Despite normal serum zinc levels, the patient showed AE symptoms like dermatitis and alopecia, with zinc dysregulation indicated by reduced alkaline phosphatase. Genetic testing revealed maternal and paternal SLC39A4 variants affecting zinc transporter function. Treatment with oral zinc and topical crisaborole resolved symptoms in 2 weeks. The study emphasizes the importance of genetic testing over biochemical markers for AE diagnosis and the need for early zinc supplementation and antiviral prophylaxis in patients at risk for KVE. It also highlights the necessity of SLC39A4 sequencing and HSV testing in persistent acral dermatitis cases to guide treatment.
55 citations
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September 2020 in “Frontiers in Bioengineering and Biotechnology” Engineered MOFs show promise for better wound healing but need more research for human use.
10 citations
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November 2015 in “Elsevier eBooks” Modern wound dressings like hydrocolloids, alginates, and hydrogels improve healing and are cost-effective.