research Faculty Opinions recommendation of A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea.
Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.
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5 / 1000+ resultsresearch Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
This study identified Activin A and its antagonist follistatin as crucial regulators of hair cell differentiation in mice, suggesting a local gradient of Activin A influences auditory sensory epithelium development.
research A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
This study identified Activin A and follistatin as key regulators of hair cell differentiation in the mammalian auditory sensory epithelium, with Activin A signaling influencing the timing and pattern of cell differentiation.
research Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear
In this review, the authors discuss how understanding and co-regulating multiple signaling pathways could lead to effective regeneration of functional hair cells, highlighting current achievements and future approaches such as small molecule drugs and gene therapy for treating sensorineural hearing loss.
research Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development
This study found that dermal EZH2 plays a crucial role in controlling fibroblast differentiation by regulating Wnt/β-catenin and retinoic acid signaling during skin development.
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