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research Studies on Neurosteroids XXV: Influence of a 5α-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism

61 citations, September 2008 in “Biological & Pharmaceutical Bulletin”

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites

18 citations, March 2020 in “Frontiers in Neuroendocrinology”

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

$Dietary Vitamin A Impacts Refractory Telogen$

research Dietary Vitamin A Impacts Refractory Telogen

6 citations, February 2021 in “Frontiers in Cell and Developmental Biology”

Eating too much or too little vitamin A can cause hair loss.

research Management of Hair Loss Associated with Endocrine Therapy in Patients with Breast Cancer: An Overview

7 citations, May 2016 in “SpringerPlus”

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

research Effect of the 5α-Reductase Enzyme Inhibitor Dutasteride in the Brain of Intact and Parkinsonian Mice

16 citations, October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Dutasteride may protect the brain in early Parkinson's disease.

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Community Join

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community 9 months of minoxidil , finasteride, spironolactone, estradiol

in Progress Pictures 63 upvotes 5 months ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 9 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community 4months fin and dermarolling prog

in Progress Pictures 7 upvotes 6 months ago

User shares progress after 4 months of using finasteride and dermarolling, with occasional use of coconut and rosemary oil. They aim to stop hair loss and hope for increased top density.

community March 22 – jan 23 fin 1mg minoxidil 5% every few days . 22 male .

in Update 614 upvotes 1 year ago

Jamesdunn8811 has been using a combination of finasteride and minoxidil to treat his hair loss over the past four months, with successful results. He has experienced no side effects and noticed increased thickness and baby hairs growing in both temples.

community My hair loss theory and what I did to stop my hair loss. 6 years of stabilization.

in Treatment 8 upvotes 4 years ago

A user shared their personal theory on hair loss, suggesting it's caused by reduced blood flow and scalp calcification rather than DHT, and claimed to have stopped their hair loss by massaging the scalp, using acid peels, and applying oils and copper peptides. They have not noticed further hair loss for six years since starting this routine.

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