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Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Eating too much or too little vitamin A can cause hair loss.

Dutasteride may protect the brain in early Parkinson's disease.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Treatment during development affects hormone balance and sexual behavior in male rats.

Patterned hair loss is relatively common in women and not usually a sign of serious health issues.

Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Vitamin D receptor is crucial for skin wound healing.

Phospholipase A2 enzymes play key roles in skin health and disease.

Excess androgens may cause PCOS, not just be a symptom.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Vegetable protein lowers cholesterol and protein deficiency can cause health issues.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

DHT, a testosterone byproduct, causes male pattern baldness.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.