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GlossaryCollagen Synthesis

process of creating collagen, crucial for skin and hair structure

Collagen synthesis, also known as collagen formation or collagen production, is the process by which the body produces collagen, a vital protein that provides structure and strength to skin, hair, nails, bones, and connective tissues. This process involves the assembly of amino acids into procollagen, which is then modified and assembled into mature collagen fibers, essential for maintaining the integrity and elasticity of various tissues.

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Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

48 citations, May 2015 in “NPJ microgravity”

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

research Oncostatin M Is Upstream of JAK-STAT Signaling During the Murine Hair Cycle

April 2016 in “Journal of Investigative Dermatology”

Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.

Anti-Aging Potential of Gypenosides Fraction Obtained from Naturally Grown Gynostemma Pentaphyllum in Ulleungdo Island and Its Seven New Gypenosides

research Anti-Aging Potential of Gypenosides Fraction Obtained from Naturally Grown Gynostemma Pentaphyllum in Ulleungdo Island and Its Seven New Gypenosides

April 2016 in “Journal of Investigative Dermatology”

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

research Connective Tissue Sheath of Hair Follicle Is a Major Source of Dermal Type I Procollagen in Human Scalp

4 citations, September 2012 in “Journal of dermatological science”

The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.

research Dermal Niche Signaling and Epidermal Stem Cells

January 2019 in “Advances in stem cells and their niches”

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

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community So does oral minoxidil age your skin or not

in Minoxidil 41 upvotes 8 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

128 upvotes 6 years ago

Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.