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research Psychiatric and sexual dysfunction warnings strengthened for finasteride and dutasteride

January 2026 in “Pharmaceutical journal/The pharmaceutical journal”

The MHRA announced on 11 May 2026 that it will update the product information for finasteride and dutasteride to include more details on potential psychiatric and sexual side effects, following a review of existing evidence.

research Medical treatments for balding in men.

5 citations , April 1999 in “PubMed”

This source notes that topical minoxidil and oral finasteride can modestly maintain or regrow hair in men with androgenic alopecia, especially at the scalp vertex, with minimal side effects.

research Finasteride-Induced Neuropsychiatric Reactions

February 2026 in “Journal of Dermatology and Skin Science”

This review suggests a causal relationship between finasteride, used for hair loss, and persistent neuropsychiatric side effects like depression, citing evidence that fulfills key causality criteria and calls for cautious use along with strengthened regulatory oversight.

research Exercise in the management of polycystic ovary syndrome: A position statement from Exercise and Sports Science Australia

2 citations , May 2024 in “Journal of science and medicine in sport”

This position statement reviews the role of exercise professionals in managing PCOS and provides recommendations for physical activity, but it reports no new clinical findings.

research Prescription Appropriateness of Cyproterone Acetate/Ethinylestradiol in Primary Care: A Population-Based Study in Italy

3 citations , April 2017 in “Clinical Drug Investigation”

The researchers concluded that after the 2013 EMA recommendation, there was an overall reduction in CPA/EE prescriptions, but no substantial change in patient diagnoses or potential concurrent hormonal contraceptive use.

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community What ketoconazole shampoo do you use?

in Ketoconazole 6 upvotes 1 year ago

Users discuss ketoconazole shampoos for hair loss, mentioning Nizoral, selsun blue, and alternatives like prescription strength options and compounded lotions to reduce dryness. Some users suggest using finasteride and minoxidil instead, questioning the cost-benefit of ketoconazole.

community 18m, already balding. Is a hair system the way to go? I don’t have the strength to go bald this young

in Hair Systems 148 upvotes 8 months ago

An 18-year-old with early hair loss is advised to consider minoxidil and finasteride, with a doctor's consultation recommended. Alternatives like a hair system or shaving are suggested due to potential medication side effects and lifelong commitment.

community Progress after 5 months of 0.5 mg Dutasteride and 2.5 Mg oral minoxidil. I am considering a transplant eventually so strengthening the base area and doner areas. Suggestions on if I should continue the dosage for sometime before opting for a transplant or should I immediately go for it?

in Progress Pictures 34 upvotes 1 year ago

OP is using 0.5 mg Dutasteride and 2.5 mg oral Minoxidil for hair loss and considering a hair transplant. Most users suggest waiting 1-2 years to maximize results from the medication before opting for a transplant.

community Passive/preventative anti-DHT haircare routine?

in Treatment 2 upvotes 1 year ago

The conversation discusses preventative hair care measures for hair loss, focusing on non-prescription treatments like rosemary, peppermint, castor oils, microneedling, and ketoconazole shampoo. It also touches on the use of finasteride, minoxidil, and RU58841 for those experiencing hair loss.

community Help in Germany to get recommended medicine

in Finasteride/Dutasteride 5 upvotes 2 years ago

A user in Germany is seeking advice on obtaining Dutasteride, Minoxidil, and Biotin for hair treatment before a hair transplant. They face difficulties getting prescriptions and are concerned about delays due to required exams.

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learn Ketoconazole

Is there a difference between 1% and 2% ketoconazole? The documented differences are strength and supply: 1% ketoconazole shampoo is sold over the counter while 2% is usually prescription-only, and almost all of the trial evidence — including a 2015 Cochrane review — was gathered on the 2% shampoo rather than in a head-to-head comparison of the two strengths.
Ketoconazole: Do I need a prescription to buy it? You can buy low-concentration ketoconazole over the counter, but higher concentrations require a prescription.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Overview

learn Dutasteride

Can I use dutasteride without a prescription? All about its sale and regulations. Dutasteride requires a prescription and cannot be used without medical supervision.
Is it dangerous to buy dutasteride without a prescription? Buying dutasteride without a prescription is dangerous due to potential serious health risks.

learn Cyproterone

Do I need a prescription to take cyproterone? Cyproterone acetate is a prescription-only medicine in every country that licenses it, and it has no FDA approval in the United States — regulators require a prescriber because the drug needs hormonal and liver monitoring and carries a dose-related meningioma risk flagged by the EMA in 2020.

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