10 citations
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September 2007 in “Pediatrics in Review” This review discusses the hormonal and pathological factors contributing to gynecomastia and premature thelarche in children but presents no new clinical findings; the authors emphasize the need for careful evaluation.
1 citations
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March 2025 in “Archivos Argentinos de Pediatria” This study found that exposure to phytoestrogens, bisphenol A, parabens, and phthalates was associated with developing idiopathic premature thelarche in girls.
July 2020 in “Research Square (Research Square)” This study found that girls with isolated premature thelarche, confirmed by GnRH stimulation test, aged 4-8 years, may have significantly advanced bone age, with obesity and serum IGF-1 and DHEAS levels being key risk factors.
July 2020 in “Research Square (Research Square)” In this study, researchers found that girls aged 4-8 years with isolated premature thelarche had significantly advanced bone age, with obesity and elevated serum IGF-1 SDS and DHEAS SDS being key independent risk factors.
2 citations
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January 2000 in “Pediatrics in review” This article discusses diagnostic evaluations and management strategies for isosexual precocious puberty, emphasizing the importance of accurate identification and appropriate treatment, but it provides no new clinical findings.