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GlossaryNeutrophils (Polymorphonuclear leukocytes)

white blood cells that engulf and destroy pathogens

Neutrophils, also known as polymorphonuclear leukocytes (PMNs), are a type of white blood cell that plays a crucial role in the body's immune response. They are the first responders to sites of infection, where they engulf and destroy pathogens through a process called phagocytosis. Neutrophils are characterized by their multi-lobed nuclei and granular cytoplasm, which contains enzymes that help break down invading microbes.

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research Inhibition of the Pro-Oxidant Effects of Benoxaprofen on Polymorphonuclear Leucocytes by Retinol Acetate In Vitro

2 citations , July 1982 in “British Journal of Dermatology”

Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.

research Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-Mediated Root Sheath Disruption in Advance of Overt Hair Loss

37 citations , November 2003 in “Veterinary pathology”

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus

research The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus

18 citations , September 1990 in “Veterinary Dermatology”

Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.

research Chemotaxis in Psoriasis

January 1989 in “Journal of The American Academy of Dermatology”

Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.

research Cell Surface B2m-Free Human Leukocyte Antigen Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?

3 citations , July 2023 in “Biomolecules”

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

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