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    GlossaryPohl-Pinkus constrictions

    narrow, weakened areas on hair shafts from growth disruptions

    Pohl-Pinkus constrictions are narrow, weakened areas along the hair shaft that can occur due to temporary disruptions in hair growth, often caused by physical or emotional stress, illness, or nutritional deficiencies. These constrictions can make the hair more prone to breakage and are sometimes used as indicators of past physiological stress in trichological examinations.

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      Trichoscopy of Alopecia Areata: An Update

      research Trichoscopy of alopecia areata: An update

      89 citations , March 2018 in “The Journal of Dermatology”
      Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

      research Dermoscopic And Clinical Features Of Alopecia Areata In Pakistani Patients: A Cross-Sectional Study

      January 2025 in “Journal of Rawalpindi Medical College”
      The study on 800 Pakistani patients with Alopecia Areata, conducted at THQ Hospital Layyah, found that the condition affects both genders almost equally, with 52.9% females and 47.1% males. The scalp was the most common site, observed in 89.9% of cases. Dermoscopic examination revealed yellow dots in 79.9% of patients, black dots in 33.1%, exclamation mark hairs in 42.5%, and other features like short villus hairs, broken hairs, pigtail hairs, and Pohl-Pinkus constriction. A significant correlation was found between age and these dermoscopic features, with most patients being young, aged 10-30.

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      community PG causing irritation when applying RU

      in Research/Science 2 years ago
      The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

      community Pp405 phase 2a clinical results

      in Research/Science  38 upvotes 9 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 2 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.