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This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.

In this study, combining Polynucleotides High Purification Technology with hyaluronic acid significantly reduced atrophic post-acne scar areas and improved Goodman-Baron scores in a majority of treated patients over six months, reaffirming the approach's beneficial effects in a real-world outpatient setting.

This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.

This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.

This study observed that both polynucleotides (PN HPT™) and platelet-rich plasma (PRP) improved hair density and quality in men with androgenetic alopecia, with comparable outcomes and no significant adverse events.