Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.

In this study, combining Polynucleotides High Purification Technology with hyaluronic acid significantly reduced atrophic post-acne scar areas and improved Goodman-Baron scores in a majority of treated patients over six months, reaffirming the approach's beneficial effects in a real-world outpatient setting.

This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.

This study found that Plinest injections improved skin hydration and elasticity in the face, neck, and décolleté and were well-tolerated, with high patient satisfaction over a 4-month follow-up.

This study observed that both polynucleotides (PN HPT™) and platelet-rich plasma (PRP) improved hair density and quality in men with androgenetic alopecia, with comparable outcomes and no significant adverse events.

This review compares DNA-derived biopolymers, PN and PDRN, in dermatology, emphasizing their distinct molecular characteristics and roles, and reports no new clinical results.

This study found that individualized homeopathic medicine can significantly improve outcomes in patients with alopecia areata, including complete hair regrowth and reduced SALT scores within 5 to 12 months, without relapse, and shows promise for alopecia universalis through targeted miasmatic and constitutional remedies.

This study reported that patients with mild to detectable androgenetic alopecia showed subjective improvement and a favorable safety profile after receiving a polynucleotide-based intradermal gel, with only one case of mild injection-site erythema noted among 60 participants over three months.

This study found that bio fabricated herbal silver nanoparticles from Blumea lacera extracts demonstrated significant antibacterial activity against Staphylococcus aureus and Escherichia coli, and notable anti-inflammatory effects, though their antioxidant capacity was insignificant compared to the extract.

This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.

This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.

This narrative review examines advancements in regenerative aesthetic medicine, focusing on injectable modalities like PRP, polynucleotides, and exosomes, but highlights the need for more robust evidence and standardization in clinical applications.

This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.

In this article, the authors describe a successfully treated case of a newborn with ichthyosis using a neonatal protocol involving an incubator with controlled temperature and humidity, sepsis prevention, eye protection, and emollient care without keratolytics during the early neonatal period.

This study discusses how polynucleotide-based cosmetic products can improve aging skin in patients with particular morphotypes by restoring cellular metabolism, enhancing microcirculation, and promoting intracellular matrix remodeling, offering potential benefits for reversing chrono- and photo-aging and aiding tissue recovery after cosmetic or surgical procedures.

This study highlights the underexplored allergenic potential of Trichophyton rubrum, a dermatophyte, which can trigger IgE-mediated allergic reactions and a Th2 immune response shift, underscoring the need for its inclusion in diagnostic panels and further research for treating chronic mycoses and related allergies.

This study conducted among sex workers in Kostanay reported a low HIV prevalence of 0.8% but a high syphilis rate of 15.6%, highlighting significant social risks and emphasizing the need to expand pre-exposure prophylaxis and prevention programs.

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.

This review discusses the ethnobotanical uses and phytochemistry of Plumbago zeylanica L., highlighting its potential pharmacological benefits for conditions such as diabetes and cardiovascular disorders, but reports no new experimental findings.

This review summarizes the antioxidant and anticarcinogenic properties of Indian Gooseberry, its phytochemical composition, and its use in traditional Ayurvedic medicine, but reports no new clinical results.

The study highlights Teak's (Tectona grandis) diverse applications beyond high-quality timber, emphasizing its bioactive compounds' pharmacological potential in cancer treatment and other uses across traditional medicine, cosmetics, and biodiesel production.

In this study, thyroid disorders were found to significantly affect physical and emotional well-being, with notable prevalence in married, urban, and non-working participants in South India.

In this study, researchers identified a gene regulatory network in Arabidopsis that controls root hair growth under low-temperature conditions, revealing specific transcription factors and downstream targets that contribute to this growth response despite overall plant development being halted.

This study characterized the physical-chemical properties of Eclipta alba and identified compounds in the plant that could support its use in developing hair loss treatments.

This study found that intradermal polynucleotide injections were linked to improvements in the appearance around the eyes and increased patient satisfaction, with minimal adverse effects, suggesting potential for further research to validate efficacy and optimize treatment protocols.

This source highlighted the promising potential of polynucleotides in aesthetic medicine but emphasized the need for rigorous, high-quality studies to validate their effectiveness and safety.

This review discusses the regenerative potential of polynucleotides and polydeoxyribonucleotides in aesthetic medicine, noting their benefits for skin texture, hydration, and patient satisfaction despite limited high-quality evidence.

In this study, researchers formulated a topical gel containing β-sitosterol for alopecia treatment and found it demonstrated good 5 alpha reductase inhibitory activity in vitro, comparable to a commercial product, indicating its potential for further antiandrogenic activity investigation.

This review highlights that various commonly prescribed medications for chronic conditions may impact male fertility by affecting hormone secretion, sperm production, ejaculation, erectile function, and libido, although conclusive evidence is limited to specific drug groups.