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GlossaryPoly(lactic-co-glycolic acid) (PLGA)

biodegradable polymer used in medical and pharmaceutical applications

Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable and biocompatible polymer commonly used in medical and pharmaceutical applications, such as drug delivery systems and tissue engineering. It gradually breaks down into lactic acid and glycolic acid, which are naturally metabolized by the body, making it an ideal material for temporary implants and controlled-release medications.

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research Skin Permeability and Transdermal Delivery Route of 50-nm Indomethacin-Loaded PLGA Nanoparticles

39 citations , August 2017 in “Colloids and Surfaces B: Biointerfaces”

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

research Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia

22 citations , March 2020 in “Cosmetics”

Nanotechnology improves minoxidil treatment for hair loss.

research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles

4 citations , July 2023 in “Pharmaceutics (Basel)”

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

research Promoting Effect of Type 17 Collagen Production by Chlorogenic Acid Using PLGA Nanoparticles in Human Epidermal Keratinocyte Cells

8 citations , February 2020 in “Journal of Drug Delivery Science and Technology”

Encapsulating chlorogenic acid in nanoparticles boosts type 17 collagen production, potentially aiding skin care.

research Dual Growth Factor Releasing Multi-Functional Nanofibers for Wound Healing

355 citations , August 2013 in “Acta Biomaterialia”

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community 7 years on FIN (Success Story)

in Progress Pictures 50 upvotes 1 year ago

A 30-year-old male successfully improved hair density over 7 years using finasteride, minoxidil, microneedling, and recently added dutasteride. He experienced no side effects and noticed significant regrowth, especially after adding minoxidil and microneedling.