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research Loss of PIKFyve Kinase Function Driven by Platelet Factor 4 Promoter Results in Platelet Lysosomal Storage Defects and Infiltration of Multiple Organs with Vacuolated Macrophages

November 2011 in “Blood”

This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.

research Influence of an iplatelant therapy with P2Y12 receptor inhibitors on platelet function in elderly patients with acute coronary syndrome

May 2024 in “International journal of medicine and psychology.”

This study found that elderly patients with acute coronary syndrome had higher PRU rates, and ticagrelor showed greater antiplatelet efficacy compared to clopidogrel in this population.

research Platelet-Rich Plasma and Combination Therapies for Dry Eye Disease: Current Advances and Future Directions

1 citations , October 2025 in “Transfusion Medicine and Hemotherapy”

This review synthesizes current evidence on platelet-rich plasma for dry eye disease and reports no new results; the authors emphasize the need for standardized trials to validate these approaches.

research Functional Regulation of Adipose-Derived Stem Cells by PDGF-D

69 citations , October 2014 in “Stem Cells”

This study found that PDGF-D acts as a potent mitogenic factor in adipose-derived stem cells, enhancing their proliferation, migration, and growth factor expression, suggesting its use as a preconditioning agent for ASC transplantation.

research Functional hair follicle regeneration: an updated review

42 citations , February 2021 in “Signal Transduction and Targeted Therapy”

This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.

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community CHECKLIST: Blood and other test before starting treatment

4 upvotes 2 years ago

Before starting hair loss treatment, it's suggested to undergo various blood and health tests to minimize side effects. The checklist includes tests for kidney function, liver enzymes, blood sugar, vitamins, hormones, and more.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

90 upvotes 6 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Hair loss from sickness 2 month update , progress ?

in Is this regrowth? 17 upvotes 1 year ago

The user experienced significant hair loss due to health issues and has only taken vitamins for recovery. They are seeking advice on regrowth progress after two months.

community 1 year 3 months on Finasteride - Still improving!

in Progress Pictures 362 upvotes 1 year ago

A user in their early twenties shared progress after 1 year and 3 months on 1mg daily oral finasteride, reporting no side effects and improvements despite initial shedding. They emphasized the importance of early intervention and noted that results come in waves, with shedding followed by regrowth.

community Growth factors, VEGF, And more,possible permanent cure for people with moderate hairloss?

3 upvotes 1 year ago

The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.

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