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research Different Keratin Polypeptides in Epidermis and Other Epithelia of Human Skin: A Specific Cytokeratin of Molecular Weight 46,000 in Epithelia of the Pilosebaceous Tract and Basal Cell Epitheliomas

277 citations , October 1982 in “The Journal of Cell Biology”

Basal-cell epitheliomas and the pilosebaceous tract share a unique keratin, distinguishing them from other skin areas.

research The Human Keratins: Biology And Pathology

1398 citations , May 2008 in “Histochemistry and Cell Biology”

Keratins are crucial for cell stability, wound healing, and cancer diagnosis.

Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

10 citations , October 1993 in “Archives of dermatological research”

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

research Histochemical Observations of Lectin-Binding Sites and Keratin Distribution in Calcifying Epithelioma of Malherbe

6 citations , January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.

A Monoclonal Antibody Established from the Immunization of Basal Cell Carcinoma Tissues Reacts to the Intercellular Space of Basal Cell Carcinoma and Hair Follicles

research A Monoclonal Antibody Established from the Immunization of Basal Cell Carcinoma Tissues Reacts to the Intercellular Space of Basal Cell Carcinoma and Hair Follicles

1 citations , November 2002 in “Journal of dermatology”

The antibody created from BCC tissues reacts similarly to both BCC and hair follicles, suggesting BCC may come from hair follicle cells.

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community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

in Research/Science 4 upvotes 1 week ago

Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

community Why liposomal finasteride and minoxidil may be better than traditional topical solutions.

in Research/Science 2 upvotes 8 months ago

Liposomal formulations of finasteride and minoxidil may enhance drug delivery to the skin and hair follicles more effectively than traditional solutions, potentially improving treatment outcomes. However, more human clinical trials are needed to confirm these benefits.

community The theory that explains everything. The malloclusion theory has been proven.

in Research/Science 27 upvotes 2 years ago

Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 3 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 3 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.