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Dose-Dependent Histopathological and Structural Impact of Chemical Hair Straighteners on Scalp Epithelium and Hair Fibers Using Albino Wistar Rats

research Dose-Dependent Histopathological and Structural Impact of Chemical Hair-Straighteners on Scalp Epithelium and Hair-Fibres Using Albino Wistar Rats

September 2025 in “Sahel Journal of Life Sciences FUDMA”

This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.

research Scalp Micro-Pigmentation via Transcutaneous Implantation of Flexible Tissue Interlocking Biodegradable Microneedles

3 citations , October 2019 in “Pharmaceutics”

This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.

research Melanocytes: The new Black

93 citations , October 2006 in “The International Journal of Biochemistry & Cell Biology”

This review discusses melanocyte biology and its genetic and molecular basis, highlighting its relevance in understanding diseases like vitiligo and albinism, and reports no new findings.

research An in vivo method for the detection of somatic mutations at the cellular level in mice

11 citations , February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis”

This study reports that treatment with X-rays or procarbazine induced dose-dependent mutations in melanocytes in mouse hair follicles, showing similar mutation rates to previous methods.

research The effects of gamma rays on the regeneration of hair follicles are carried over to later hair cycles

5 citations , November 2015 in “International Journal of Radiation Biology”

This study suggests that gamma-ray irradiation affects hair follicle density, structure, and pigmentation in mice, with some changes observed in later hair cycles.

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Community Join

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community Finasteride - 5 years and my expierience

128 upvotes 1 week ago

A 26-year-old shared their 5-year experience using finasteride and minoxidil for hair loss, noting initial improvements but later experiencing reduced libido and erection quality, leading them to switch from oral to topical finasteride. They advise starting with a low-dose topical solution and emphasize making informed decisions, acknowledging that while finasteride is effective, it can have side effects.

community Where to buy Latanaprost or equivalent?

2 upvotes 11 months ago

The conversation discusses using Latanoprost for hair regrowth, with the original poster seeking advice on where to purchase it without a prescription. Users suggest alternatives like Triple Hair's TH-07, which includes Finasteride, Minoxidil, and Latanoprost, and Strut's Latanoprost with melatonin and caffeine.

community Major dutasteride hairline recession

4 upvotes 4 weeks ago

The user experienced hairline recession after switching from finasteride to dutasteride and increasing the dosage. They plan to start using oral minoxidil and are advised to be patient as shedding is expected during the transition.

community 16 Month Progress (0 month, 6 month, 16 month)

1654 upvotes 7 months ago

A user shared their 16-month hair regrowth progress using finasteride, oral minoxidil, and micro-needling, noting significant improvement and minor side effects like stray ear hairs. Consistency in treatment was emphasized, with noticeable hair improvement within the first 6 months.

community When do I know when to switch from fin to dut? (3 month comparison)

in Finasteride/Dutasteride 1 upvotes 7 months ago

The user has been using finasteride and minoxidil for hair loss but is considering switching to dutasteride due to insufficient results, particularly for hairline improvement. Other users shared their experiences with dutasteride, noting potential benefits and side effects, and suggested a gradual transition from finasteride to dutasteride.

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Learn

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Scalp Micropigmentation

What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Are the pigments used in scalp micropigmentation safe? Providers describe SMP pigments as safe, medical-grade and made for the scalp, but those are supplier and clinic descriptions rather than regulatory approvals: no colour additive is approved for injection into the skin, and allergic reactions to tattoo pigment are documented.

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Clinics

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