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research Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

321 citations , March 2015 in “Nature”

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.

research Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.

277 citations , October 1982 in “The Journal of Cell Biology”

This study found that the cytokeratin patterns in skin epithelia can distinguish between different types, with basal-cell epitheliomas showing a striking similarity to the pilosebaceous tract.

research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

260 citations , June 2011 in “Cell”

This study found that Wnt signaling in the hair follicle is crucial for coordinating the behavior of epithelial and melanocyte stem cells, which drives hair regeneration and melanocyte differentiation in mice.

research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation

240 citations , April 2011 in “Pigment Cell & Melanoma Research”

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

research Critical Stages of Hair Development and Pigmentation in the Mouse

236 citations , January 1951 in “Physiological zoology”

Hair growth and pigmentation in mice involve specific stages crucial for research.

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community Pills for life Dutasteride 2.5mg+5mg oral Minoxidil 🤑

in Satire 37 upvotes 1 year ago

The conversation discusses using Dutasteride, oral Minoxidil, and other medications for hair loss, with the user expressing satisfaction despite potential side effects. The user prefers these treatments to maintain a youthful hairline, despite others suggesting alternative methods.

community Piroctone olamine effective and better than ketoconazole?

2 upvotes 1 year ago

Piroctone olamine may be more effective and gentler than ketoconazole for dandruff and itchiness. Users report better results with piroctone olamine, but it is less available in the US.

community Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways

11 upvotes 2 years ago

Pilose antler extracts may promote hair growth in androgenetic alopecia by activating hair follicle stem cells through the AKT and Wnt pathways. However, results in mice may not directly apply to humans due to differences in genetic and biochemical conditions.

community UK Shampoo recs - Piroctone Olamine

1 upvotes 2 years ago

Piroctone Olamine at 1% is recommended for reducing scalp inflammation and encouraging hair growth. The user seeks recommendations for UK shampoos/conditioners containing this ingredient.

community Any recent developments with Piloscopy?

3 upvotes 2 years ago

Piloscopy's impact on hair loss treatment after 10 years remains unclear, and peppermint oil has shown to be effective, similar to minoxidil, in stopping recent hair loss. The user is considering dermarolling and has concerns about hair transplant scars.

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