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Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

research Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

26 citations , February 1998 in “Chemico-Biological Interactions”

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases

59 citations , February 1998 in “Chemico-Biological Interactions”

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles

46 citations , January 1991 in “Journal of Investigative Dermatology”

Minoxidil works in liver and outer hair root sheath for hair growth.

research Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation

16 citations , May 1992 in “Journal of Investigative Dermatology”

Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.

research Sulfation of Minoxidil by Liver Sulfotransferase

66 citations , September 1982 in “Biochemical Pharmacology”

Liver enzyme helps minoxidil work better for blood vessel relaxation.

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community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 738 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 10 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community The theory that explains everything. Please help me make this big!

in Research/Science 2446 upvotes 4 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community What is the consensus on topical tretinoin mono therapy?

in Research/Science 8 months ago

The conversation discusses the effectiveness of topical tretinoin as a monotherapy for hair loss, with users suggesting it may not be as effective as minoxidil or finasteride. The original poster is considering other options like a phenol peel and is concerned about the risks of derma rolling.

community Foods with sufficient procyanidin b2?

in Treatment 7 upvotes 4 years ago

Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Conversation focuses on foods with sufficient procyanidin b2, such as dark chocolate and apples, and the required dosage.

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