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      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.
      Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      community Compunded Oral Minoxidil, As Efficient As Tablet Variants?

      in Minoxidil  146 upvotes 10 months ago
      The user discusses using compounded oral minoxidil due to the ineffectiveness and inconvenience of topical minoxidil for diffuse thinning. They question the efficacy of compounded minoxidil compared to original tablet forms and express concerns about the importance of excipients and binders.

      community Just had my first dermatologist appointment - unsure on Oral Minox vs Compounded Min/Fin/Tret (while already on Dut)

      in Minoxidil  2 upvotes 1 year ago
      A 28-year-old male, previously on dutasteride for hair loss, is considering oral minoxidil or a compounded treatment of minoxidil, finasteride, and tretinoin after noticing hairline recession. The dermatologist suggested oral minoxidil and mentioned a compounded option, but the user is unsure about its benefits compared to current treatments.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 11 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Is there a hidden cure out there?

       1595 upvotes 2 months ago
      There is skepticism about conspiracy theories claiming pharmaceutical companies hide cures for profit. Treatments like finasteride and dutasteride are mentioned as affordable options for hair loss.

    Learn

    5 / 800 results

      learn GT20029

      Investigational compound designed to degrade androgen receptors in the scalp; not approved or sold anywhere.

      learn Clascoterone

      An androgen-receptor blocker approved only for acne (Winlevi 1% cream). A scalp solution is still investigational for hair loss; its sponsor reports positive Phase III results in men, not yet peer-reviewed.

      learn Pyrilutamide

      Pyrilutamide (KX-826) is an investigational topical antiandrogen. It is not approved anywhere, and its trial results, including a failed 2023 Phase III and a positive 2026 one, are sponsor-reported and not peer-reviewed.

      learn KX-826

      • Kintor Pharmaceutical: KX-826, a New Name in Hair Loss Research KX-826 (pyrilutamide) is an experimental topical androgen receptor blocker from Kintor Pharmaceutical and is not approved as a medicine anywhere. Its first China Phase III trial did not beat placebo; the company reported in March 2026 that a later Phase III of a 1.0% formulation met its primary endpoint, but these results are company announcements, not peer-reviewed, and long-term safety is unknown.