research Progranulin, a secreted tumorigenesis and dementia-related factor, regulates mouse hair growth 7 citations , December 2008 in “Journal of Dermatological Science” Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
research Serum Progranulin and Insulin Resistance Evaluation in Male Androgenetic Alopecia Patients March 2022 in “Benha Journal of Applied Sciences” This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.