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research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations , October 2008 in “Journal of medicinal chemistry”

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

11 citations , May 2010 in “Journal of Medicinal Chemistry”

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer

17 citations , January 2015 in “MedChemComm”

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

research Miniaturization of Sebaceous Glands: A Novel Histopathological Finding in Pemphigus Vulgaris and Pemphigus Foliaceus of the Scalp

9 citations , June 2017 in “Journal of Cutaneous Pathology”

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.

research Persistent Pemphigus Vulgaris and Pemphigus Foliaceus Showing Features of Tufted Hair Folliculitis on the Scalp

March 2019 in “Nasza Dermatologia Online”

A rare scalp condition with hair loss was correctly diagnosed and treated, leading to hair regrowth.

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Community Join

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community Whats the goal pf Nizoral and Ketoconzole shampoos?

in Ketoconazole 9 upvotes 1 year ago

Ketoconazole shampoos are primarily for dandruff and fungus but may aid hair growth slightly, though results are minor compared to finasteride and minoxidil. Users report it helps with scalp health and inflammation, but it can dry out hair if used too often.

community I can’t believe my eyes, I’m pretty sure those weren’t here

in Is this regrowth? 61 upvotes 1 year ago

User noticed new baby hairs on temples after 1.5 months of minoxidil and 1 month of finasteride. They use a topical combo, derma stamp, rosemary oil, scalp massages, and keto shampoo.

community Hair Loss Ruins Your Mind: 10x rate of BDD. PF S is not real

in Research/Science 39 upvotes 1 month ago

Hair loss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.

community Is this VIOFAIRY Minoxidil brand good

in Minoxidil 2 upvotes 1 year ago

A user has been using a new brand of minoxidil called VIOFAIRY for six months and finds it effective, though the labeling has misspellings. They are seeking feedback from others who have tried this brand.

community 16 year old Hairloss, Min for 6 months

Tarq_Hossain in General 81 upvotes 7 months ago

A 16-year-old noticed hair thinning on the crown and sides of the head, with minimal temple thinning. After using Minoxidil for 6 months, some areas improved, but the crown worsened, and they seek advice on the irregular hair loss and treatment options.

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