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research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations, October 2008 in “Journal of medicinal chemistry”

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer

17 citations, January 2015 in “MedChemComm”

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery

11 citations, May 2010 in “Journal of Medicinal Chemistry”

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo

research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo

1 citations, January 2013 in “MedChemComm”

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

research Inhibitory Activities of Puerariae Flos Against Testosterone 5α-Reductase and Its Hair Growth Promotion Activities

34 citations, August 2011 in “Journal of Natural Medicines”

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

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Community Join

5 / 11 results

community I can’t believe my eyes, I’m pretty sure those weren’t here

in Is this regrowth? 61 upvotes 2 months ago

User noticed new baby hairs on temples after 1.5 months of minoxidil and 1 month of finasteride. They use a topical combo, derma stamp, rosemary oil, scalp massages, and keto shampoo.

community Is this VIOFAIRY Minoxidil brand good

in Minoxidil 2 upvotes 4 months ago

A user has been using a new brand of minoxidil called VIOFAIRY for six months and finds it effective, though the labeling has misspellings. They are seeking feedback from others who have tried this brand.

community How it’s going so far,I’ve been using fin and minox so far for a year this is the results

in Progress Pictures 36 upvotes 1 year ago

The conversation is about a person's experience with hair loss treatment using finasteride and minoxidil for a year, and then seeing improved results after adding RU58841. They suggest shaving the head before starting RU58841 to better track progress.

community 2 years difference, has being on finasteride for a year helped? Second is after

in Progress Pictures 241 upvotes 1 year ago

The post is about a user's progress with hair loss and the effectiveness of finasteride as a treatment. The conclusion is that the user did not see any progress with their hair loss after being on finasteride for a year.

community Dermastamp only with carrier/essential oil blend

in Microneedling 15 upvotes 1 year ago

A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

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