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GlossaryPeyronie's disease

condition causing curved, painful erections due to penile scar tissue

Peyronie's disease, also known as Induratio penis plastica (IPP), is a condition characterized by the development of fibrous scar tissue inside the penis, leading to curved, painful erections. This can result in difficulties with sexual intercourse and may be associated with erectile dysfunction. The exact cause is not well understood, but it is believed to involve trauma or injury to the penis, possibly combined with genetic factors.

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research Post-Finasteride Syndrome: An Underestimated Phenomenon

May 2017 in “Urology and andrology”

Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.

research The Use of Stromal Vascular Fraction in the Treatment of Male Sexual Dysfunction: A Review of Preclinical and Clinical Studies

11 citations, June 2018 in “Sexual medicine reviews”

Stromal Vascular Fraction might help with male sexual dysfunction, but more research is needed to confirm its safety and effectiveness.

Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024

research Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024

August 2024 in “medRxiv (Cold Spring Harbor Laboratory)”

Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.

research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases

2 citations, May 2022 in “International Journal of Impotence Research”

Finasteride may be linked to Peyronie’s disease, but more research is needed.

research Topical Minoxidil in the Treatment of Male Erectile Dysfunction

28 citations, May 1994 in “The Journal of Urology”

Topical minoxidil not effective for erectile dysfunction treatment.

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community First time using hair fibers until the Rogaine kicks in.

in Product 89 upvotes 1 year ago

The conversation is about a user trying hair fibers to cover hair loss while waiting for Rogaine (Minoxidil) to work. Some suggest using Finasteride or other treatments for better results, while others criticize the appearance of the fibers.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 677 upvotes 4 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 3 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

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