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This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.

This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.

This study found that the contribution of the hair follicle pathway to skin permeation of chemicals can be predicted using lipophilicity, with hydrophilic chemicals showing greater permeation reduction from hair follicle plugging than lipophilic ones.

This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.

This study found that porcine skin serves as a reliable model for studying drug absorption into human hair follicles, showing a strong correlation in follicular drug absorption between porcine and human skin.