57 citations
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May 1986 in “Clinics in endocrinology and metabolism” This review found that women with idiopathic hirsutism may have increased 5α-reductase activity, as indicated by elevated levels of a dihydrotestosterone-reduced metabolite, but more research is needed to confirm its clinical relevance as a biomarker.
June 2013 in “International Journal of Dermatology” This study found that among HIV-infected women, central lipohypertrophy was associated with shorter eyelashes but not changes in scalp hair texture or inflammation.
45 citations
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August 2010 in “Hormone Molecular Biology and Clinical Investigation” This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.
November 2025 in “Open Access CRIS of the University of Bern” This study compared serum and hair steroid hormone profiles in adolescents and found that hair steroid profiling is a feasible, non-invasive alternative to serum analysis, with androgen levels in both mediums correlating more strongly with body size and composition in boys than in girls.
November 2025 in “European Journal of Endocrinology” This study found that hair steroid profiling is a feasible, non-invasive alternative to serum analysis in adolescents, with androgen levels correlating more strongly with body size and composition in boys than girls.