11 citations
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January 2006 in “Drug development and industrial pharmacy” In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.
This study observed that chitosan-decorated PS404-b-PAA63 nanoparticles may enhance skin retention and reduce permeation flux of finasteride, suggesting potential for improved transdermal delivery.
2 citations
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December 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that low frequency sonophoresis may reduce percutaneous absorption of sodium fluorescein-loaded liposomes by partially blocking follicular pathways in the skin.
82 citations
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January 2002 in “Journal of drug targeting” This study found that drug delivery through human scalp skin may be more effective for lipophilic and hydrophilic drugs compared to abdominal skin, highlighting the potential of intrafollicular delivery methods.
6 citations
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December 2015 in “International journal of nanomedicine” This study found that low-frequency sonophoresis significantly decreased the skin penetration of sodium fluorescein-loaded PEGylated liposomes with D-limonene and affected percutaneous absorption by partially plugging hair follicle orifices.