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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 1 month ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 4 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community The amazing fast pace of PP405.

      in Chat  322 upvotes 1 month ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  107 upvotes 8 months ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.