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GlossaryPhosphodiesterase Inhibitors (PDEIs)

block enzymes that break down cyclic nucleotides

Phosphodiesterase Inhibitors (PDE Inhibitors or PDEIs) are a class of drugs that block the action of phosphodiesterase enzymes, which are responsible for breaking down cyclic nucleotides like cAMP and cGMP. By inhibiting these enzymes, PDE inhibitors can increase the levels of these cyclic nucleotides, leading to various therapeutic effects such as vasodilation, anti-inflammatory actions, and improved cardiac function. These drugs are used to treat conditions like erectile dysfunction, pulmonary hypertension, and certain types of heart failure.

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learn Neem Oil

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research Phosphodiesterase Inhibitors and Prostaglandin Analogues in Dermatology: A Comprehensive Review

9 citations , December 2020 in “Dermatologic Therapy”

Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.

research Faculty Opinions Recommendation of Treatment of Recurrent Priapism in Sickle Cell Anemia with Finasteride: A New Approach

January 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Finasteride may be a promising treatment for recurrent priapism in sickle cell anemia.

research Lower Urinary Tract Symptoms: What’s New in Medical Treatment?

22 citations , January 2018 in “European urology focus”

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

research Comment on ‘Androgenetic Alopecia Is Associated with Increased Scalp Hardness’: Role of Phosphodiesterase Inhibitors?

1 citations , April 2020 in “Journal of The European Academy of Dermatology and Venereology”

Drugs like PDEI may help hair disorders like AGA.

research Application of LncRNA-miRNA-mRNA CeRNA Network Analysis in the Treatment of Androgenic Alopecia

1 citations , December 2022 in “PubMed”

The lncRNA LOXL1-AS1 may help diagnose and treat androgenic alopecia.

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community 39m 1.1mg finasteride 3mg oral minoxidil

in Progress Pictures 17 upvotes 2 years ago

A user shared their progress using 1.1mg oral finasteride and 3mg oral minoxidil since January 2024, noting significant improvement without side effects. They previously had an allergic reaction to topical treatments.

community Help in Germany to get recommended medicine

in Finasteride/Dutasteride 5 upvotes 1 year ago

A user in Germany is seeking advice on obtaining Dutasteride, Minoxidil, and Biotin for hair treatment before a hair transplant. They face difficulties getting prescriptions and are concerned about delays due to required exams.

community Soon nearly 2 Years Finasteride+Minoxidil Update

in Progress Pictures 406 upvotes 2 years ago

The conversation is about a user sharing a nearly 2-year update on hair regrowth using finasteride and minoxidil, with occasional use of microneedling. Commenters are impressed with the significant improvement in the user's hair.

community I am finally giving up on my hair

in Shaved/buzzed 57 upvotes 2 years ago

User tried Minoxidil and Finasteride for hair loss with no success and considers giving up. Others suggest continuing treatment, trying hair transplant, or embracing baldness.

community Hair energiser tablets, useful or not?

in Product 1 year ago

A user is unsure if "Hair Energiser" tablets are effective for hair growth after a year of use. Replies suggest using finasteride instead and call the tablets a scam.

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