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    GlossaryPhosphodiesterase Inhibitors (PDEIs)

    block enzymes that break down cyclic nucleotides

    Phosphodiesterase Inhibitors (PDE Inhibitors or PDEIs) are a class of drugs that block the action of phosphodiesterase enzymes, which are responsible for breaking down cyclic nucleotides like cAMP and cGMP. By inhibiting these enzymes, PDE inhibitors can increase the levels of these cyclic nucleotides, leading to various therapeutic effects such as vasodilation, anti-inflammatory actions, and improved cardiac function. These drugs are used to treat conditions like erectile dysfunction, pulmonary hypertension, and certain types of heart failure.

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      community Help in Germany to get recommended medicine

      in Finasteride/Dutasteride  5 upvotes 7 months ago
      A user in Germany is seeking advice on obtaining Dutasteride, Minoxidil, and Biotin for hair treatment before a hair transplant. They face difficulties getting prescriptions and are concerned about delays due to required exams.

      community 39m 1.1mg finasteride 3mg oral minoxidil

      in Progress Pictures  17 upvotes 1 year ago
      A user shared their progress using 1.1mg oral finasteride and 3mg oral minoxidil since January 2024, noting significant improvement without side effects. They previously had an allergic reaction to topical treatments.

      community Stop wasting your time with BS products

      in Treatment  412 upvotes 1 month ago
      Effective treatments for hair loss include finasteride, dutasteride, RU58841, and minoxidil. Starting treatment early is important, and users discuss different brands, forms, and side effects.

      community Hair energiser tablets, useful or not?

      in Product 1 year ago
      A user is unsure if "Hair Energiser" tablets are effective for hair growth after a year of use. Replies suggest using finasteride instead and call the tablets a scam.

      community Soon nearly 2 Years Finasteride+Minoxidil Update

      in Progress Pictures  406 upvotes 1 year ago
      The conversation is about a user sharing a nearly 2-year update on hair regrowth using finasteride and minoxidil, with occasional use of microneedling. Commenters are impressed with the significant improvement in the user's hair.