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GlossaryPeripheral Blood Mononuclear Cells (PBMC)

blood cells with a single round nucleus, like lymphocytes and monocytes

Peripheral Blood Mononuclear Cells (PBMCs) are a type of blood cell that has a single round nucleus, such as lymphocytes (T cells, B cells, NK cells) and monocytes. These cells are crucial for the immune system, as they play key roles in immune response and are often used in research and clinical studies to understand various diseases, including autoimmune disorders and infections.

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Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy

research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy

4 citations , July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.

research Apoptosis Resistance in Peripheral Blood Lymphocytes of Alopecia Areata Patients

38 citations , September 2004 in “Journal of Autoimmunity”

Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.

research MicroRNA-Enriched Exosomes from Different Sources of Mesenchymal Stem Cells Can Differentially Modulate Functions of Immune Cells and Neurogenesis

29 citations , December 2021 in “Biomedicines”

Exosomes from different stem cell sources affect immune cells and brain cell growth differently.

research Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege

27 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

Somatostatin may help protect hair follicles from immune attacks.

research Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation

7 citations , January 2022 in “Biomedicines”

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

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