research 572 Development of immunotherapies targeting TCR-Vβ2 for treatment of cutaneous T cell lymphoma
Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.
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5 / 1000+ resultsresearch Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
This review discusses recent advances in understanding Merkel cell carcinoma biology, including the development of genetically-engineered mouse models and potential therapeutic targets, but reports no new clinical results.
research Three-dimensional models: from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
This review discusses the potential of 3D cell cultures, particularly Patient-Derived Organoids, in advancing research on liposarcoma by addressing limitations of 2D cultures and animal models but reports no new experimental findings.
research Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice
This study found that human adipose tissue-derived mesenchymal stem cells inhibited A549 tumor growth but significantly promoted HT-29 tumor growth in mouse models, highlighting opposing effects depending on the cancer type.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.
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