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research Long-term treatment with finasteride induces apoptosis and pathological changes in female mice

3 citations , April 2019 in “Human & Experimental Toxicology”

This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.

The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus

research The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus

18 citations , September 1990 in “Veterinary Dermatology”

This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.

research Regression of Pathologic Changes Induced by the Long-term Administration of Contraceptive Steroids to Rodents

20 citations , June 1985 in “Toxicologic Pathology”

In this study, prolonged high-dose steroid treatment in rats caused several pathological changes, some of which regressed, particularly improvements in mammary gland tumors and pituitary-related symptoms, after stopping treatment.

research Dynamic evaluation of pathological changes in a mouse acne model by optical imaging technology

2 citations , May 2023 in “Experimental dermatology”

In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.

research An Update on Pathological Changes in Canine Demodicosis

June 2026 in “Journal of Advances in Biology & Biotechnology”

In this study conducted at the Veterinary Clinical Complex in Bikaner, Rajasthan, researchers found that among 240 canine dermatitis cases, 25 dogs had demodicosis, characterized by various hematological and serum biochemical changes, and distinctive histopathological alterations in skin samples.

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community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

78 upvotes 5 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

community 2 years of 5% topical minoxidil + 1 year of 1mg finasteride.

in Progress Pictures 236 upvotes 5 months ago

The user shared progress pictures after using 5% topical minoxidil for two years and 1mg finasteride for one year, but many commenters believe the hair looks the same, attributing changes to different haircuts rather than actual regrowth. The user reported no side effects from finasteride, and opinions varied on whether any significant hairline improvement occurred.

community How to reverse "Dutasteride face"?

7 upvotes 8 months ago

The user experienced facial puffiness after switching from finasteride to dutasteride, which they believe is due to dutasteride. They are seeking advice on reversing this effect, considering factors like diet, exercise, and potential hormonal changes.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community A Study I came along by mistake researching (Dutasteride +Pumpkin seed oil ) for every other day use.

16 upvotes 3 months ago

Alternating Dutasteride with pumpkin seed oil may protect the spleen from damage caused by Dutasteride. Pumpkin seed oil's antioxidants help counteract oxidative stress and immune suppression.

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