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GlossaryParathyroid Hormone-related Protein

regulates calcium levels and influences bone development

Parathyroid Hormone-related Protein (PTHrP) is a protein that plays a crucial role in regulating calcium levels in the body, similar to parathyroid hormone (PTH). It is involved in various physiological processes, including the development of bones and the regulation of cellular growth and differentiation. PTHrP is also significant in certain medical conditions, such as hypercalcemia of malignancy, where it can be produced in excess by some types of cancer cells.

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research Clinical Uses for Calciotropic Hormones 1,25-Dihydroxyvitamin D3 and Parathyroid Hormone-Related Peptide in Dermatology: A New Perspective

23 citations, April 1996 in “PubMed”

Vitamin D3 and parathyroid hormone-related peptide may have important uses in skin treatments.

research Parathyroid Hormone-Related Peptide and the Hair Cycle: Is It the Agonists or the Antagonists That Cause Hair Growth?

9 citations, July 2014 in “Experimental Dermatology”

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

research Drug Armamentarium for Alopecia Areata

February 2021 in “Journal of pharmaceutical and biological sciences”

No cure exists for alopecia areata, and treatments are personalized.

research Hair Biology

33 citations, August 2018 in “Facial Plastic Surgery Clinics of North America”

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

research Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin

33 citations, May 2006 in “Journal of Investigative Dermatology”

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

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