July 2026 in “International Journal of Applied Pharmaceutics”
This review discusses the dermatological and systemic adverse effects of hair dye use, particularly focusing on the common allergen para-phenylenediamine, and reports no new clinical data.
This case report indicates that contact dermatitis on the face can result from using a bleaching ointment containing ammonium bisulfite during hair-dyeing.
1 citations
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March 2025 in “Archivos Argentinos de Pediatria”
This study found that exposure to phytoestrogens, bisphenol A, parabens, and phthalates was associated with developing idiopathic premature thelarche in girls.
188 citations
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October 2012 in “The AAPS Journal”
This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.
Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.
a synthetic cortisol used for anti-inflammatory effects
How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it?The over-the-counter hydrocortisone label sets the limits: a thin film on the affected patch, no more than three or four times a day, and no longer than seven days without a doctor's direction — and the scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.
Can hydrocortisone be used together with other treatments like minoxidil or steroid injections?Clinicians do use a mild steroid cream to settle the scalp irritation minoxidil can cause, but no verified trial tests hydrocortisone added to minoxidil or to corticosteroid injections, and prolonged scalp use risks skin thinning — combining it is a decision to take with a prescriber.
What are the risks of long-term hydrocortisone use on the scalp?Dermatology reviews describe long-term topical corticosteroid use as causing skin thinning, delayed healing, greater infection risk, possible suppression of the body's own cortisol, and rebound flares on stopping — and over-the-counter hydrocortisone labels limit use to about a week without a doctor's direction.