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research Rationale and design of the GLADE study: a randomized, multicenter, double-blind, placebo-controlled trial evaluating the safety and efficacy of gestrinone subdermal bioabsorbable pellet in endometriosis-related pelvic pain

July 2025 in “Annals of Medicine”

This study describes a planned multicenter randomized controlled trial to assess the safety, tolerability, and pharmacokinetics of subdermal gestrinone pellets in patients with deep infiltrative endometriosis-related pelvic pain, but it does not report any findings yet.

research Management of Gout: Targeting Pain or Metabolic Control

April 2026 in “International Journal of Research and Review”

This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.

A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

research A randomized placebo-controlled multicentre study to evaluate the safety and efficacy of finasteride for male chronic pelvic pain syndrome (category IIIA chronic nonbacterial prostatitis).

127 citations , May 2004 in “PubMed”

This randomized pilot study suggests that finasteride may benefit some men with category IIIA chronic pelvic pain syndrome, although it is not recommended as monotherapy unless benign prostatic hyperplasia is also present.

research A Randomized Placebo-Controlled Multicentre Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

6 citations , March 2005 in “The Journal of Urology”

This study evaluates finasteride's safety and efficacy for treating male chronic pelvic pain syndrome, but the abstract does not report any results.

research Effects of finasteride in patients with inflammatory chronic pelvic pain syndrome: a double-blind, placebo-controlled, pilot study

65 citations , March 1999 in “Urology”

This study found that finasteride significantly reduced symptom severity scores in patients with inflammatory chronic pelvic pain syndrome, though its effect on pain was not significant.

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Learn

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learn Hair Transplant

How can I manage pain after a hair transplant? Use prescribed medications, over-the-counter pain relievers, and cold compresses to manage pain.
How much pain will I be in after a hair transplant surgery? Pain after a hair transplant is usually mild to moderate and manageable with medication.
Will I feel pain during a hair transplant? Most patients feel minimal discomfort during a hair transplant due to local anesthesia.
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learn Overview

learn Scalp Micropigmentation

Will I experience pain after the scalp micropigmentation treatment? You may feel discomfort during the procedure and soreness afterward.

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Community Join

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community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

in Treatment 3 upvotes 1 year ago

RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.

community Do I enjoy microneedling too much?

in Satire 26 upvotes 1 year ago

The conversation is about the use of microneedling, specifically with a derma stamp, for hair regrowth. Users discuss their experiences, pain levels, and the satisfaction of taking control over hair loss, with some mentioning the use of Minoxidil to enhance results.

community Control your blood pressure - for me this was my root issue

9 upvotes 1 year ago

Managing blood pressure can help with hair loss, as seen with the use of medications like Cialis and oral minoxidil, which improved hairline and blood pressure. Lifestyle changes, such as reducing stimulant use and adjusting testosterone replacement therapy (TRT) doses, also play a role in addressing hair loss and overall health.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Why are we using 1.5mm for microneedling? Evidence says we don't need to.

39 upvotes 4 months ago

Shorter microneedle lengths, like 0.5mm, may be more effective and safer for hair regrowth than longer ones, such as 1.5mm, which can cause more pain and risk. Users report success with various regimens, including minoxidil, finasteride, and other topicals, alongside microneedling.

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Clinics

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Experts

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65
Hair System Specialist
Suparno Paine
Kolkata, West Bengal, India

Suparno Paine