August 2026 in “Adolescencia e Saude” This narrative review found a strong association between oxidative stress and the severity of alopecia areata, noting that increased oxidant and reduced antioxidant biomarkers correlate with higher disease severity scores, and emphasizes the need for larger prospective studies for clinical validation.
December 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that patients with female pattern hair loss had higher oxidative stress levels and lower antioxidant enzyme activities than healthy controls, suggesting oxidative stress may play a key role in disease progression.
May 2021 in “Open Access Macedonian Journal of Medical Sciences” This study found that individuals with premature hair graying had significantly lower levels of antioxidants compared to controls, but the severity of graying did not significantly correlate with oxidative stress levels.
September 2025 in “Turkish Journal of Dermatology” This study found that children with alopecia areata had higher levels of oxidative stress markers but showed no significant differences in depression and suicide tendencies compared to healthy peers.
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October 2022 in “Clinical Cosmetic and Investigational Dermatology” In this study, SNPs in genes affecting skin pigmentation were linked to each skin type's unique response to environmental stress, suggesting potential for personalized skin care products.